Tyrosinase is a copper-binding enzyme involved in melanin biosynthesis.However, the detailed structure of human tyrosinase has not yet been solved, along with the identification toyota benify of the key sites responsible for its catalytic activity.We used site-directed mutagenesis to identify the residues critical for the copper binding of human ty
Reliability management is one of the primary concerns in manycore systems design.Different aging mechanisms such as Negative-Bias Temperature Instability (NBTI), Electromigration (EM), and thermal cycling (TC) can reduce the reliability of these systems.However, state-of-the-art works mainly focused on NBTI and EM, whereas a few works have consider
As neural circuits form, growing processes select the correct synaptic partners through interactions between cell surface proteins.The presence of such proteins on two neuronal processes may lead to either adhesion or repulsion; however, the consequences of mismatched expression have rarely been explored.Here, we show 15-fc0093dx that the Drosophil
The coastal wetlands in the Yellow River Delta play a vital role in the ecological function of the area.However, the impact of primary restoration on microbial communities is not yet fully understood.Hence, this study aimed to analyze the bacterial and archaeal communities in the soil.The results indicated that Marinobacter and Halomonas were predo
Since the merger, few attempts have been made to interrogate the role of leadership on the operational stability of the new university.By employing a qualitative approach, this study allowed the participants to construct an accurate and, in-depth account of what really transpired during and after the merger.A case study design was used to focus int